Related Experiment Video

Updated: May 26, 2026

Modeling Multiple Sclerosis in the Two Sexes: MOG35-55-Induced Experimental Autoimmune Encephalomyelitis
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Modeling Multiple Sclerosis in the Two Sexes: MOG35-55-Induced Experimental Autoimmune Encephalomyelitis

Published on: October 13, 2023

Sex differences and genomics in autoimmune diseases

Shashi Amur1, Ameeta Parekh, Padmaja Mummaneni

  • 1Office of Clinical Pharmacology, Center for Drug Evaluation and Research, Food and Drug Administration, Silver Spring, MD 20903, USA. Shashi.amur@fda.hhs.gov

Journal of Autoimmunity
|December 30, 2011
PubMed
Summary

Autoimmune diseases (AIDs) affect multiple systems, with women disproportionately affected. Genetic factors, including the MHC locus and PTPN22 gene, significantly influence AID susceptibility across diverse populations.

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