Abnormal anandamide metabolism in celiac disease

Natalia Battista1, Antonio Di Sabatino, Monia Di Tommaso

  • 1Department of Biomedical Sciences, University of Teramo, Teramo, Italy. nbattista@unite.it

Summary

Celiac disease shows increased anandamide synthesis due to higher N-acylphosphatidyl-ethanolamine specific phospholipase D (NAPE-PLD) activity in the duodenal mucosa. Gluten exposure further enhances this enzyme

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