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Related Concept Videos

Cancer Survival Analysis01:21

Cancer Survival Analysis

Cancer survival analysis focuses on quantifying and interpreting the time from a key starting point, such as diagnosis or the initiation of treatment, to a specific endpoint, such as remission or death. This analysis provides critical insights into treatment effectiveness and factors that influence patient outcomes, helping to shape clinical decisions and guide prognostic evaluations. A cornerstone of oncology research, survival analysis tackles the challenges of skewed, non-normally...
What is Cancer?02:12

What is Cancer?

Cells and tissues must meticulously coordinate their activities for the normal functioning of the human body. Therefore, they exhibit socially responsible behavior - resting, growing, dividing, differentiating, or dying - for the organism’s benefit. Cancer arises when cells divide uncontrollably and invade other tissues or organs.
Although people have known about cancer for centuries, it was only in 1761 that Giovanni Morgagni of Padua performed a detailed autopsy of patients who died from...
What is Cancer?02:12

What is Cancer?

Cells and tissues must meticulously coordinate their activities for the normal functioning of the human body. Therefore, they exhibit socially responsible behavior - resting, growing, dividing, differentiating, or dying - for the organism’s benefit. Cancer arises when cells divide uncontrollably and invade other tissues or organs.
Although people have known about cancer for centuries, it was only in 1761 that Giovanni Morgagni of Padua performed a detailed autopsy of patients who died from...
Cancer Prevention02:59

Cancer Prevention

Several factors can increase the risk of cancer in an individual. About 50% of cancer cases can be prevented by adopting a healthy lifestyle, regular exercise, eating healthy, and following a modest cancer prevention diet. Epidemiological studies have consistently shown that populations with vegetable and fruit-rich diets have reduced the incidence of cancer. On the other hand, populations who have a diet rich in animal fat, red meat, junk food, or high calories are predisposed to cancer.
Some...
Cancer Prevention02:59

Cancer Prevention

Several factors can increase the risk of cancer in an individual. About 50% of cancer cases can be prevented by adopting a healthy lifestyle, regular exercise, eating healthy, and following a modest cancer prevention diet. Epidemiological studies have consistently shown that populations with vegetable and fruit-rich diets have reduced the incidence of cancer. On the other hand, populations who have a diet rich in animal fat, red meat, junk food, or high calories are predisposed to cancer.
Some...
Cancer02:18

Cancer

Cancers arise due to mutations in genes involved in the regulation of cell division, which leads to unrestricted cell proliferation. Modern science and medicine have made great strides in the understanding and treatment of cancer, including eradicating cancer in some patients. However, there is still no cure for cancer. This is largely due to the fact that cancer is a large group of many diseases.

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Updated: May 25, 2026

Comparison of Predictive Performance of Three Lymph Node Staging Systems in Colorectal Signet Ring Cell Carcinoma Based on Machine Learning Model
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Comparison of Predictive Performance of Three Lymph Node Staging Systems in Colorectal Signet Ring Cell Carcinoma Based on Machine Learning Model

Published on: April 18, 2025

Cancer statistics, 2012.

Rebecca Siegel1, Deepa Naishadham, Ahmedin Jemal

  • 1Surveillance Research, American Cancer Society, Atlanta, GA 30303-1002, USA. Rebecca.siegel@cancer.org

CA: a Cancer Journal for Clinicians
|January 13, 2012
PubMed
Summary
This summary is machine-generated.

Cancer incidence is stable in women and declining in men, with significant decreases in cancer death rates across most groups. Continued application of cancer control knowledge can accelerate progress.

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Competing-Risk Nomogram for Predicting Cancer-Specific Survival in Multiple Primary Colorectal Cancer Patients after Surgery
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Competing-Risk Nomogram for Predicting Cancer-Specific Survival in Multiple Primary Colorectal Cancer Patients after Surgery

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Comparison of Predictive Performance of Three Lymph Node Staging Systems in Colorectal Signet Ring Cell Carcinoma Based on Machine Learning Model
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Competing-Risk Nomogram for Predicting Cancer-Specific Survival in Multiple Primary Colorectal Cancer Patients after Surgery
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Competing-Risk Nomogram for Predicting Cancer-Specific Survival in Multiple Primary Colorectal Cancer Patients after Surgery

Published on: September 27, 2024

Area of Science:

  • Oncology
  • Public Health
  • Epidemiology

Background:

  • The American Cancer Society annually estimates cancer incidence and mortality in the U.S.
  • Data are compiled from multiple national sources including the National Cancer Institute and Centers for Disease Control and Prevention.
  • Cancer statistics provide crucial insights into disease burden and trends.

Purpose of the Study:

  • To present the latest cancer statistics for the United States.
  • To analyze trends in cancer incidence, mortality, and survival.
  • To identify disparities and opportunities for cancer control.

Main Methods:

  • Utilized incidence data from the National Cancer Institute, CDC, and North American Association of Central Cancer Registries.
  • Employed mortality data from the National Center for Health Statistics.
  • Analyzed trends over specific periods, including 2004-2008 and 1999-2008.

Main Results:

  • Projected 1,638,910 new cancer cases and 577,190 deaths in 2012.
  • Cancer incidence stable in women, declining 0.6% annually in men (2004-2008).
  • Cancer death rates decreased 1.8% annually in men and 1.6% in women (2004-2008).
  • Significant declines in death rates observed across racial/ethnic groups, except American Indians/Alaska Natives.
  • Lung, colorectum, breast, and prostate cancer death rates continue to decline.
  • Lung cancer contributed significantly to overall decline in men; breast cancer in women.
  • Over 1 million cancer deaths avoided since 1990/1991.

Conclusions:

  • Cancer death rates are declining overall, with notable progress in specific demographics.
  • Targeted cancer control interventions are essential, particularly for underserved populations.
  • Continued surveillance and application of evidence-based strategies are vital for further reducing cancer burden.