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Teratogenicity

Teratogenicity

The ability of a drug to produce structural deformations and functional abnormalities in the developing embryo or the fetus is called teratogenicity, and the drug producing this effect is known as a teratogen. Teratogenic effects include stillbirth, miscarriage, intrauterine growth restriction, and neurocognitive delay. A teratogen may affect the embryo at different stages of development, which is important in determining the type and extent of the damage. During blastocyst formation, the early...

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Related Experiment Video

Updated: May 25, 2026

Fate Mapping of Human Embryonic Stem Cells by Teratoma Formation

Fate Mapping of Human Embryonic Stem Cells by Teratoma Formation

Published on: August 1, 2010

[Homunculus: Fetiform teratoma].

N Joutel¹, N Pirot, I Pop

¹Service de gynécologie obstétrique, CHU, 1, rue de Germont, 76000 Rouen, France. nicjout@hotmail.com

Gynecologie, Obstetrique & Fertilite

|January 28, 2012

Summary

This summary is machine-generated.

Ovarian teratomas called homunculus are rare, highly differentiated tumors resembling malformed fetuses. This report details the clinical, pathological, and imaging characteristics of this unusual ovarian tumor.

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Last Updated: May 25, 2026

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Area of Science:

Gynecologic Oncology
Pathology
Radiology

Background:

Ovarian teratomas are germ cell tumors, with dermoid cysts being the most common.
Homunculus is an exceedingly rare subtype of mature cystic teratoma, characterized by its unique fetal-like appearance.

Observation:

This case highlights a rare homunculus ovarian teratoma.
The tumor presented with specific clinical symptoms, pathological findings, and imaging features.

Findings:

Pathological examination confirmed a highly differentiated teratoma with fetal-like structures.
Imaging studies (e.g., ultrasound, CT, MRI) revealed characteristic features aiding in diagnosis.

Implications:

Understanding the distinct features of homunculus teratomas is crucial for accurate diagnosis and management.
Increased reporting of such rare cases contributes valuable data to the literature.