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Updated: May 25, 2026
02:28
Measuring Psoriasis Severity at Home
Published on: March 1, 2024
Current and relevant concepts in psoriatic arthritis.
Claudia Goldenstein-Schainberg1, Maria Helena Sampaio Favarato, Roberto Ranza
1Disciplina de Reumatologia, Universidade de São Paulo. cgs@usp.br
Revista Brasileira De Reumatologia
|January 31, 2012
Summary
Psoriatic arthritis (PsA) is a complex joint disease impacting quality of life. Early diagnosis and treatment, including biologics, improve outcomes for PsA patients.
Area of Science:
- Rheumatology and Immunology
Background:
- Psoriatic arthritis (PsA) is a systemic, polymorphic joint disease with variable presentation and clinical course.
- Outcomes are influenced by comorbidities like diabetes, hypertension, and dyslipidemia.
- Early diagnosis is crucial, especially with subtle skin manifestations.
Purpose of the Study:
- Discuss new concepts in immunogenetics, pathophysiology, and clinical/therapeutic aspects of PsA.
- Emphasize factors affecting quality of life and life expectancy.
- Highlight new treatment guidelines and the role of GRAPPA.
Main Methods:
- Extensive literature review (PubMed, Lilacs).
- Analysis of clinical experience.
Main Results:
- Progressive erosive disease affects up to 50% of patients.
- Anti-TNF biologics enable inflammation control, particularly in enthesitis and axial PsA.
- GRAPPA facilitates collaborative research between rheumatologists and dermatologists.
Conclusions:
- Delayed diagnosis and treatment negatively impact PsA prognosis.
- Biologics have significantly improved inflammatory control in PsA.
- Multidisciplinary collaboration, as promoted by GRAPPA, is vital for advancing PsA management.
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