Related Experiment Video
Updated: May 25, 2026

Live Cell Imaging of Alphaherpes Virus Anterograde Transport and Spread
Published on: August 16, 2013
Infection of cells by alphaviruses
Dennis T Brown1, Raquel Hernandez
1Department of Molecular and Structural Biochemistry, North Carolina State University, Raleigh, NC 27695, USA. dennis_brown@ncsu.edu
Abstract:
It is widely accepted that alphaviruses enter cells by a process involving endocytosis and low-pH-mediated virus membrane-cell membrane fusion. This model and the data supporting it have received extensive and numerous reviews. The major points presented in support of this model are summarized briefly herein. It is the primary objective of this review to present an alternative mechanism describing the penetration of cells by alphaviruses which does not involve endocytosis or exposure to acid environment. The data supporting this model are summarized in detail.
More Related Videos
Related Concept Videos
Viruses of Archaea
Immune Response Against Viral Pathogens
NK Cells
NK cells are a crucial part of our innate immune system, acting as the first line of defense against viral infections. These cells can recognize and kill infected cells without prior exposure to the virus, effectively slowing down the spread of infection. Additionally, NK cells produce proinflammatory...
Viral Recombination
Viral Hepatitis I: Introduction
Viruses with RNA Genomes
What are Viruses?

