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Updated: May 25, 2026
08:50
A Murine Model of Fetal Exposure to Maternal Inflammation to Study the Effects of Acute Chorioamnionitis on Newborn Intestinal Development
Published on: June 24, 2020
First trimester complications.
A Ildiko Martonffy1, Kirsten Rindfleisch, Anne Marie Lozeau
1Department of Family Medicine, University of Wisconsin School of Medicine and Public Health, 1100 Delaplaine Court, Madison, WI 53715, USA. ildi.martonffy@fammed.wisc.edu
Primary Care
|February 8, 2012
Summary
Early pregnancy symptoms like vaginal bleeding and pain require prompt evaluation for potential complications such as ectopic pregnancy. Healthcare providers should consider gestational trophoblastic disease and discuss nausea treatments.
Area of Science:
- Obstetrics and Gynecology
- Early Pregnancy Complications
Background:
- Vaginal bleeding, abdominopelvic pain, nausea, and vomiting are frequent symptoms in early pregnancy.
- All women of reproductive age with these symptoms require pregnancy evaluation.
Purpose of the Study:
- To highlight the importance of evaluating women of reproductive age for pregnancy when presenting with abdominal/pelvic pain or vaginal bleeding.
- To emphasize the need for a high index of suspicion for ectopic pregnancy.
- To consider gestational trophoblastic disease and discuss nausea management.
Main Methods:
- Clinical evaluation of women presenting with symptoms suggestive of early pregnancy complications.
- Diagnostic investigation for the cause of vaginal bleeding.
- Discussion of treatment options for nausea.
Main Results:
- Common presenting symptoms in early pregnancy include vaginal bleeding, abdominopelvic pain, nausea, and vomiting.
- Ectopic pregnancy should be suspected in women with abdominal pain and bleeding around 7 weeks of amenorrhea.
- Gestational trophoblastic disease is a potential cause of bleeding.
Conclusions:
- Prompt evaluation for pregnancy is crucial in women of reproductive age with relevant symptoms.
- Early suspicion and investigation of ectopic pregnancy are vital.
- Management should include considering gestational trophoblastic disease and addressing nausea symptoms.
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