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Procedures for In Vitro Cultivation of Treponema pallidum, the Syphilis Spirochete
Published on: January 24, 2025
[Syphilitic orchitis: a case report].
Nobuyuki Sekita1, Rika Nishikawa, Masaaki Fujimura
1The Department of Urology, Chibaken Saiseikai Narashino Hospital.
Hinyokika Kiyo. Acta Urologica Japonica
|February 21, 2012
Summary
This case report details a rare instance of syphilitic orchitis in Japan, a tertiary syphilis manifestation. Diagnosis involved imaging and serological tests, confirming granulomatous inflammation caused by syphilis.
Area of Science:
- Urology
- Infectious Diseases
- Pathology
Background:
- Tertiary syphilis is a rare condition in contemporary Japan.
- Syphilitic orchitis, an inflammation of the testis due to syphilis, is an uncommon presentation.
Observation:
- A patient in his early forties presented with left scrotal swelling.
- Ultrasonography revealed a 30 mm low echoic nodule within the scrotal contents.
- Tumor markers (AFP, LDH, hCG) were normal, but serological tests (TPHA, RPR) were strongly positive.
Findings:
- High orchiectomy was performed due to suspected testicular tumor.
- Histopathology showed non-specific granulomatous inflammation with lympho-plasmatic infiltration.
- The condition was diagnosed as granulomatous inflammation of the left testis caused by syphilis.
Implications:
- Highlights the importance of considering syphilis in the differential diagnosis of testicular masses, even in low-prevalence areas.
- Underscores the need for thorough serological testing in cases of unexplained scrotal pathology.
- Emphasizes that syphilis can present with varied and rare clinical manifestations.
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