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Updated: May 24, 2026

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DNAzyme 10-23 - Based Nanomachines for Nucleic Acid Recognition
Published on: February 9, 2024
Enzyme-free signal amplification in the DNAzyme sensor via target-catalyzed hairpin assembly
Ai-Xian Zheng1, Juan Li, Jin-Ru Wang
1The Key Lab of Analysis and Detection Technology for Food Safety of the MOE, College of Chemistry and Chemical Engineering, Fuzhou University, Fuzhou 350108, P. R. China.
Abstract:
A simple, highly sensitive and enzyme-free DNAzyme sensor based on target-catalyzed hairpin assembly is developed, which permits detection of 0.1 pM target DNA. Furthermore, this DNAzyme sensor is capable of detecting target DNA in real samples because of its high selectivity.

