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Linear interstitial keratitis: a distinct clinical entity revisited.
Charles M Calvo1, Shameema Sikder, Nick Mamalis
1University of Nevada School of Medicine, Las Vegas, NV, USA.
Cornea
|March 13, 2012
Summary
Linear interstitial keratitis is a rare corneal condition presenting as horizontal stromal infiltrates. While its cause is unknown, this study details three cases and suggests further research for better understanding.
Area of Science:
- Ophthalmology
- Corneal Diseases
Background:
- Linear interstitial keratitis is a rare corneal stromal lesion.
- Its etiology remains largely unknown in ophthalmic literature.
Observation:
- Three young adult patients presented with distinct horizontal linear stromal infiltrates.
- One case involved corneal perforation, another a visually significant scar requiring keratoplasty.
Findings:
- All patients responded successfully to topical steroid treatment.
- The condition presents as a unique clinical entity, despite variations in reported cases.
Implications:
- Further investigation using advanced imaging and serological testing is crucial.
- Understanding linear interstitial keratitis may improve diagnosis and treatment of rare corneal conditions.

