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Updated: May 24, 2026

Drug-Induced Sleep Endoscopy (DISE) with Target Controlled Infusion (TCI) and Bispectral Analysis in Obstructive Sleep Apnea
Published on: December 6, 2016
Sleep endoscopy as a diagnostic tool in pediatric obstructive sleep apnea
Mai Thy Truong1, Victoria G Woo, Peter J Koltai
1Division of Pediatric Otolaryngology, Lucile Packard Children's Hospital at Stanford, Department of Otolaryngology-Head and Neck Surgery, Stanford University School of Medicine, 801 Welch Rd, Stanford, CA 94305, USA. mtruong@ohns.stanford.edu
Sleep endoscopy effectively identifies airway obstruction in children with obstructive sleep apnea (OSA), both those with persistent symptoms after surgery and those who have not had surgery. This diagnostic tool aids in targeted surgical interventions, significantly lowering apnea-hypopnea index (AHI) scores.
Area of Science:
- Pediatric Otolaryngology
- Sleep Medicine
- Diagnostic Imaging
Background:
- Persistent obstructive sleep apnea (OSA) affects 10-20% of children post-adenotonsillectomy (T&A).
- Accurate identification of residual airway obstruction is crucial for effective treatment.
- Sleep endoscopy offers a direct visualization of the pharynx under anesthesia.
Purpose of the Study:
- To evaluate the efficacy of sleep endoscopy in identifying obstruction sites in children with persistent OSA after T&A.
- To assess the utility of sleep endoscopy in surgically naive children with OSA.
- To determine if sleep endoscopy-directed surgery improves outcomes in these pediatric populations.
Main Methods:
- Retrospective cohort study of 80 children with OSA undergoing sleep endoscopy and subsequent surgery.
- Data collected included age, BMI, comorbidities, and pre- and post-operative Apnea-Hypopnea Index (AHI).
- Paired t-test used to compare AHI before and after sleep endoscopy-directed surgery.
Main Results:
- In children with persistent OSA post-T&A (51%), mean AHI decreased significantly from 15.7 to 7.9 (p<.01) after directed surgery.
- In surgically naive children (49%), mean AHI also decreased significantly from 13.8 to 8.0 (p<.01) after sleep endoscopy-directed surgery.
- The study included 65% males with a mean age of 6 years and average BMI of 19.
Conclusions:
- Sleep endoscopy is a reliable method for pinpointing obstruction sites in children with OSA.
- It is effective for both children with persistent OSA after adenotonsillectomy and those who are surgically naive.
- This diagnostic approach facilitates targeted surgical management, leading to improved AHI scores.
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