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Related Concept Videos

Lipid-Lowering Drugs: Statins and Miscellaneous Agents01:20

Lipid-Lowering Drugs: Statins and Miscellaneous Agents

Hyperlipidemia, a medical condition often referred to as high cholesterol, is characterized by abnormally elevated levels of lipids in the bloodstream. When present in excess, these lipids, specifically cholesterol and triglycerides, can lead to serious health complications, often involving cardiovascular diseases. Illnesses like atherosclerosis, heart attacks, and pancreatitis have all been linked to untreated hyperlipidemia. This means controlling and regulating cholesterol and triglyceride...
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Antianginal Drugs: Calcium Channel Blockers and Ranolazine

Angina pectoris, a primary symptom of ischemic heart disease, requires careful pharmacological interventions. In this context, calcium channel blockers (CCBs) and ranolazine have emerged as crucial pharmacotherapeutic agents, providing deep insights into the complexities of angina management.
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Antiarrhythmic Drugs: Class IV Agents as Calcium Channel Blockers

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Sedatives and Hypnotics Drugs: Miscellaneous Agents

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Lornoxicam.

Mahrous O Ahmed1, Abdullah A Al-Badr

  • 1Department of Industrial Pharmacy, Faculty of Pharmacy, Assiut University, Assiut, Egypt.

Profiles of Drug Substances, Excipients, and Related Methodology
|April 4, 2012
PubMed
Summary
This summary is machine-generated.

This profile details lornoxicam, an NSAID for musculoskeletal and joint disorders like osteoarthritis and rheumatoid arthritis. It covers its properties, analysis, and stability for comprehensive understanding.

Related Experiment Videos

Area of Science:

  • Pharmacology and Medicinal Chemistry
  • Analytical Chemistry

Background:

  • Lornoxicam is an oxicam nonsteroidal anti-inflammatory drug (NSAID).
  • It is prescribed for musculoskeletal and joint disorders, including osteoarthritis and rheumatoid arthritis.

Purpose of the Study:

  • To create a comprehensive profile of lornoxicam.
  • To consolidate information on its description, uses, preparation, characteristics, analysis, mechanism, pharmacokinetics, reviews, and stability.

Main Methods:

  • Detailed physical characterization including ionization constant, solubility, partition coefficient, and thermal analysis.
  • Advanced analytical techniques such as X-ray powder diffraction, spectroscopy (UV, vibrational), NMR (proton and carbon-13), and mass spectrometry.
  • Analysis methods encompassing spectrophotometry, polarography, and various chromatography techniques (TLC, HPLC, HPLC-MS).

Main Results:

  • The profile compiles extensive data on lornoxicam's physical and chemical properties.
  • It outlines diverse analytical methodologies for its identification and quantification.
  • Information on its stability and pharmacokinetic profile is presented.

Conclusions:

  • This profile serves as a valuable resource for researchers and clinicians working with lornoxicam.
  • It provides a thorough overview of lornoxicam, supporting its effective use in treating inflammatory conditions.