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Cell-Free DNA Extraction of Vitreous and Aqueous Humor Specimens for Diagnosis and Monitoring of Vitreoretinal Lymphoma
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Extraocular lymphoma in the horse.

Allison T Schnoke1, Dennis E Brooks, David A Wilkie

  • 1Department of Large Animal Clinical Sciences, College of Veterinary Medicine, University of Florida, Gainesville, FL 32610, USA. alliets88@gmail.com

Veterinary Ophthalmology
|April 17, 2012
PubMed
Summary

The prognosis for equine extraocular lymphoma is fair to good with complete surgical excision, especially for nodular forms without eyelid involvement. Early diagnosis and treatment are key for positive outcomes in horses.

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Area of Science:

  • Veterinary Oncology
  • Equine Medicine
  • Ophthalmology

Background:

  • Extraocular lymphoma is a significant neoplastic condition affecting horses.
  • Understanding clinical findings and prognosis is crucial for effective management.

Purpose of the Study:

  • To detail the clinical presentation and predict the prognosis of horses diagnosed with extraocular lymphoma.
  • To identify factors influencing treatment outcomes for equine ocular tumors.

Main Methods:

  • A retrospective study analyzed medical records of 26 horses with various forms of extraocular lymphoma.
  • Data included signalment, lesion characteristics, treatments, and outcomes, with statistical analysis using Fischer's exact tests.

Main Results:

  • Complete surgical excision of lesions and absence of eyelid/cutaneous involvement correlated with better outcomes.
  • Nodular lesions showed a better prognosis than diffuse lesions.
  • Eyelid or cutaneous involvement significantly worsened the prognosis.

Conclusions:

  • Equine extraocular lymphoma has a generally fair to good prognosis, particularly with complete excision and no concurrent eyelid/cutaneous disease.
  • Nodular forms, when completely excised, offer the best outlook for remission in horses.