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Updated: Jul 21, 2026

Magnetic Resonance Imaging Quantification of Pulmonary Perfusion using Calibrated Arterial Spin Labeling
Published on: May 30, 2011
Distributions of perfusion and lung water
S U Ekeh1, R Y Chu, V J Ficken
1Department of Radiological Sciences, Veterans Affairs Medical Center, Oklahoma City, OK 73104.
Abstract:
We investigated the feasibility of using 123I-iodoantipyrine (123I-IAP) and 99mTc-labeled macroaggregated albumin (99mTc-MAA) to describe and compare the distributions of perfusion and water content in lung injuries. These radiopharmaceuticals were administered to 9 rabbits, 5 control and 4 with lung injuries. Isolated lungs were imaged by a scintillation gamma camera. The distribution of 123I-IAP outlined the entire lung mass whereas perfusion defect in the distribution of 99mTc-MAA was seen clearly in the case of severe lung injury.
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