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Disorders of Leukocytes

Disorders of Leukocytes

Leukocyte disorders can lead to either leukopenia, characterized by an abnormally low leukocyte count, or leukocytosis, marked by a very high leukocyte number.
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Classification of Leukocytes

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Updated: May 22, 2026

Assessment of the Metabolic Profile of Primary Leukemia Cells

Published on: November 21, 2018

[A leukemoid leucocytosis].

Eya Cherif¹, Ines Kechaou, Lamia Ben Hassine

¹Service de médecine interne B, Hôpital Charles Nicolle, Tunis, Tunisie. eyacherif@yahoo.fr

Annales De Biologie Clinique

|May 9, 2012

Summary

This summary is machine-generated.

Leukemoid reaction, a rare paraneoplastic syndrome, is infrequently associated with sarcoma. This case highlights a leukemoid leucocytosis revealing a uterine sarcoma, previously unreported, with a fatal outcome.

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Area of Science:

Oncology
Hematology
Pathology

Background:

Leukemoid reaction is a rare paraneoplastic syndrome.
It is commonly associated with carcinomas, particularly lung, gastric, and renal types.
Association with sarcoma is infrequent, and its occurrence in uterine sarcoma is unprecedented.

Observation:

A case of a patient presenting with significant leukocytosis was observed.
The leukocytosis was characterized as a leukemoid reaction.
This presentation was the initial indicator of an underlying malignancy.

Findings:

The leukemoid reaction was found to be a manifestation of uterine sarcoma.
This represents the first reported instance of leukemoid reaction associated with uterine sarcoma.
The condition progressed with a fatal evolution.

Implications:

This case expands the known associations of paraneoplastic leukemoid reactions.
It underscores the importance of considering rare malignancies like uterine sarcoma in the differential diagnosis of unexplained leukemoid reactions.
Highlights the need for further investigation into the mechanisms linking uterine sarcoma and paraneoplastic syndromes.