Related Experiment Video

Updated: May 22, 2026

Establishment and Propagation of Human Retinoblastoma Tumors in Immune Deficient Mice
07:55

Establishment and Propagation of Human Retinoblastoma Tumors in Immune Deficient Mice

Published on: August 4, 2011

Re: "Retinoblastoma associated orbital cellulitis"

Roman Shinder, Sergio A Ramirez, Patricia Chévez-Barrios

    Ophthalmic Plastic and Reconstructive Surgery
    |May 15, 2012
    PubMed
    Summary

    No abstract available in PubMed .

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    The Retinoblastoma Gene01:20

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    Tumor suppressor genes are normal genes that can slow down cell division, repair DNA mistakes, or program the cells for apoptosis in case of irreparable damage. Hence, they play an essential role in preventing the proliferation of damaged cells.
    The first-ever tumor suppressor gene called Rb was identified in retinoblastoma - a rare eye tumor in children. In inherited forms of the disease, a child inherits one defective copy of the Rb gene, which predisposes them to retinoblastoma. However,...