Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Open Angle Glaucoma: Treatment01:27

Open Angle Glaucoma: Treatment

In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Comparing the Use of Measured and Smoothed Data in Forecasting Visual Field Tests Using Deep Learning.

Ophthalmology science·2026
Same author

Modalities of vision restoration in optic neuropathies and retinal disease.

Progress in retinal and eye research·2026
Same author

Predicting Intraocular Pressure From Glaucoma Patients Receiving Medication Treatment Using Explainable Machine Learning.

BioMed research international·2026
Same author

Predicting Intraocular Pressure From Glaucoma Patients Receiving Medication Treatment Using Explainable Machine Learning.

BioMed research international·2026
Same author

Stimulus-driven cerebrospinal fluid dynamics is impaired in glaucoma patients.

npj aging·2026
Same author

Cerebellar dysfunction in glaucoma patients.

Brain communications·2025

Related Experiment Video

Updated: May 21, 2026

Assessing Early Stage Open-Angle Glaucoma in Patients by Isolated-Check Visual Evoked Potential
07:11

Assessing Early Stage Open-Angle Glaucoma in Patients by Isolated-Check Visual Evoked Potential

Published on: May 25, 2020

Evaluating objective and subjective quantitative parameters at the initial visit to predict future glaucomatous

Allison K Ungar1, Gadi Wollstein, Hiroshi Ishikawa

  • 1UPMC Eye Center, Eye and Ear Institute, 203 Lothrop St., Pittsburgh, PA 15213, USA.

Ophthalmic Surgery, Lasers & Imaging : the Official Journal of the International Society for Imaging in the Eye
|June 5, 2012
PubMed
Summary

Structural imaging like optical coherence tomography (OCT) can predict glaucoma progression. Baseline OCT superior quadrant retinal nerve fiber layer thickness was the strongest predictor of visual field changes in glaucoma patients.

More Related Videos

Dynamic Visual Tests to Identify and Quantify Visual Damage and Repair Following Demyelination in Optic Neuritis Patients
12:23

Dynamic Visual Tests to Identify and Quantify Visual Damage and Repair Following Demyelination in Optic Neuritis Patients

Published on: April 14, 2014

Related Experiment Videos

Last Updated: May 21, 2026

Assessing Early Stage Open-Angle Glaucoma in Patients by Isolated-Check Visual Evoked Potential
07:11

Assessing Early Stage Open-Angle Glaucoma in Patients by Isolated-Check Visual Evoked Potential

Published on: May 25, 2020

Dynamic Visual Tests to Identify and Quantify Visual Damage and Repair Following Demyelination in Optic Neuritis Patients
12:23

Dynamic Visual Tests to Identify and Quantify Visual Damage and Repair Following Demyelination in Optic Neuritis Patients

Published on: April 14, 2014

Area of Science:

  • Ophthalmology
  • Medical Imaging
  • Glaucoma Research

Background:

  • Glaucoma is a leading cause of irreversible blindness.
  • Early detection and prediction of glaucoma progression are crucial for timely intervention.
  • Structural imaging plays a role in assessing glaucoma severity and predicting disease advancement.

Purpose of the Study:

  • To evaluate the predictive ability of baseline structural imaging parameters for glaucomatous visual field progression.
  • To compare the predictive power of different imaging modalities: stereophotography, OCT, and CSLO.
  • To identify specific structural parameters most effective in forecasting visual field decline.

Main Methods:

  • 119 eyes with suspected or confirmed glaucoma underwent baseline stereophotography, OCT, and CSLO.
  • Follow-up structural and visual field data were collected over a median of 4.0 years.
  • Generalized estimating equation models were used to determine odds ratios for progression prediction.

Main Results:

  • Fifteen eyes progressed by glaucoma progression analysis, 20 by visual field index, and 10 by both.
  • Baseline parameters from stereophotographs, OCT (global, superior, inferior RNFL thickness), and CSLO were significant predictors.
  • The superior quadrant retinal nerve fiber layer thickness from OCT emerged as the single best predictor of progression.

Conclusions:

  • Baseline structural measurements from stereophotographs, OCT, and CSLO show clinical utility in predicting visual field progression in glaucoma.
  • OCT, particularly the superior quadrant RNFL thickness, demonstrates strong potential for forecasting glaucoma development.
  • These findings support the integration of advanced imaging techniques into routine glaucoma monitoring.