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Integrated Photoacoustic Ophthalmoscopy and Spectral-domain Optical Coherence Tomography
Published on: January 15, 2013
Absolute fast axis determination using non-polarization-maintaining fiber-based polarization-sensitive optical
Zenghai Lu1, Stephen J Matcher
1Department of Material Sciences and Engineering, Kroto Research Institute, University of Sheffield, Broad Lane, Sheffield S3 7HQ, UK.
Optics Letters
|June 5, 2012
Summary
This study introduces a novel calibration method for polarization-sensitive optical coherence tomography (PS-OCT) using standard optical fibers. The technique accurately determines sample Jones matrix and fast-axis orientation without specialized fiber components.
Area of Science:
- Biomedical Optics
- Optical Coherence Tomography
- Polarization Optics
Background:
- Polarization-sensitive optical coherence tomography (PS-OCT) is crucial for analyzing birefringent properties of biological tissues.
- Accurate calibration is essential for reliable PS-OCT measurements, but traditional methods often require polarization-maintaining fibers.
- Developing calibration techniques compatible with standard, non-polarization-maintaining fibers is highly desirable for broader accessibility.
Purpose of the Study:
- To present a new calibration technique for fiber-based PS-OCT systems.
- To enable accurate extraction of sample Jones matrix and fast-axis orientation.
- To demonstrate the technique's effectiveness using standard single-mode fibers.
Main Methods:
- A novel calibration method utilizing two quarter-wave plates (QWPs) in the sample arm was developed.
- The technique employs standard non-polarization-maintaining fiber (SMF-28).
- The system was implemented on a swept-source PS-OCT setup.
Main Results:
- The calibration technique accurately determines the Jones matrix of optical samples.
- Fast-axis orientation of samples can be reliably extracted.
- Successful validation was achieved using a quarter-wave plate and an equine tendon sample.
Conclusions:
- This fiber-based PS-OCT calibration method offers accurate Jones matrix and fast-axis orientation determination.
- The technique's reliance on standard SMF-28 fiber simplifies system design and reduces cost.
- It provides a robust and accessible approach for polarization-sensitive OCT imaging of biological tissues.

