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Oral intravascular papillary endothelial hyperplasia
A Buchner1, P W Merrell, W M Carpenter
1Department of Oral Pathology and Oral Medicine, School of Dental Medicine, Tel Aviv University, Israel.
Summary
Intravascular papillary endothelial hyperplasia (IPEH), a vascular lesion often mistaken for cancer, commonly presents as an organizing thrombus. This study details 16 oral IPEH cases, noting lip as the most frequent site.
Area of Science:
- Oral pathology
- Vascular lesions
- Histopathology
Background:
- Intravascular papillary endothelial hyperplasia (IPEH) is a vascular lesion typically found on the skin.
- It is often considered a manifestation of an organizing thrombus.
- IPEH can be classified as pure or mixed and is significant due to its potential misdiagnosis as angiosarcoma.
Purpose of the Study:
- To report on 16 new cases of oral Intravascular papillary endothelial hyperplasia.
- To analyze the clinical and histomorphologic features of oral IPEH.
- To highlight the diagnostic challenges and treatment of oral IPEH.
Main Methods:
- Retrospective analysis of 16 oral IPEH cases.
- Clinical feature documentation.
- Histomorphologic examination including classification into pure or mixed forms and thrombus detection.
Main Results:
- 16 oral IPEH cases were analyzed.
- 11 lesions were pure IPEH, 5 were mixed.
- Thrombi were present in all but one case.
- The lip was the most common location, followed by the tongue and buccal mucosa.
Conclusions:
- Oral IPEH is an uncommon condition.
- Histomorphologic analysis aids in classification and diagnosis.
- Local excision is the recommended treatment for oral IPEH.