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Fabrication of Amyloid-β-Secreting Alginate Microbeads for Use in Modelling Alzheimer's Disease
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Modeling brain disease in a dish: really?
Maria C Marchetto1, Fred H Gage1
1Salk Institute, 10010 North Torrey Pines Road, La Jolla, CA 92037, USA.
Cell Stem Cell
|June 19, 2012
Abstract:
Cellular programming and reprogramming technology (CPART) presents a novel approach for understanding disease progression and mechanism. In addition, CPART provides an innovative opportunity for developing diagnostic tools and novel drug candidates for therapy. In this Forum, we will discuss obstacles and solutions for modeling brain disease using CPART.
