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Published on: February 12, 2018
Amniotic membrane transplantation in primary pterygium compared with bare sclera technique
Muhammad Aamir Arain1, Muhammad Amer Yaqub, Sameer Shahid Ameen
1Department of Ophthalmology, Armed Forces Institute of Ophthalmology, Rawalpindi, Pakistan. doctorarain@yahoo.com
Summary
Amniotic membrane transplantation (AMT) significantly reduced pterygium recurrence compared to the bare sclera technique. This pilot study suggests AMT is a safe and effective treatment option for primary pterygium.
Area of Science:
- Ophthalmology
- Surgical Techniques
- Regenerative Medicine
Background:
- Pterygium is a common ocular condition.
- Recurrence after surgical excision remains a challenge.
- Bare sclera technique is a traditional method for pterygium excision.
Purpose of the Study:
- To compare the efficacy of bare sclera technique versus amniotic membrane transplantation (AMT) for primary pterygium excision.
- To evaluate the recurrence rates of pterygium following these two surgical methods.
Main Methods:
- A pilot study involving 70 patients with primary pterygium.
- Patients were divided into two groups: bare sclera excision (Group I) and excision with AMT (Group II).
- Recurrence rates were monitored for 6 months and compared using chi-square tests.
Main Results:
- Pterygium recurrence was observed in 37.5% of patients in the bare sclera group (12/32).
- Recurrence was significantly lower in the AMT group, with 12.9% of patients experiencing recurrence (4/31).
- The difference in recurrence rates between the groups was statistically significant (p = 0.025).
Conclusions:
- Amniotic membrane transplantation (AMT) following pterygium excision is a safe and effective procedure.
- AMT demonstrates a lower pterygium recurrence rate at 6 months compared to the bare sclera technique.
- AMT offers a promising alternative for managing primary pterygium with improved outcomes.
