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Peroxidase-mimic bismuth-gold nanoparticles for determining the activity of thrombin and drug screening
Chia-Wen Lien1, Chih-Ching Huang, Huan-Tsung Chang
1Department of Chemistry, National Taiwan University, 1, Section 4, Roosevelt Road, Taipei, 10617, Taiwan.
Chemical Communications (Cambridge, England)
|July 5, 2012
Abstract:
Fibrinogen-modified bismuth-gold nanoparticles (Fib-Bi-Au NPs) are prepared and used as enzyme mimics for the H(2)O(2)-mediated reaction with Amplex Red (AR), which is further employed for determining thrombin activity and drug screening.
