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Published on: October 20, 2023
Histomorphometric analysis of maxillary sinus augmentation using an alloplast bone substitute.
Roni Kolerman1, Gal Goshen, Nissan Joseph
1Department of Periodontology, Maurice and Gabriela Goldschleger School of Dental Medicine, Tel Aviv University, Tel Aviv, Israel. daniaron@netvision.net.il
Summary
This study assessed a synthetic hydroxyapatite:β-tricalcium phosphate bone graft for sinus lifts. Results show it is biocompatible and promotes new bone formation, indicating regenerative potential.
Area of Science:
- Biomaterials Science
- Regenerative Medicine
- Oral and Maxillofacial Surgery
Background:
- Sinus lift procedures are crucial for dental implantology.
- Graft materials are essential for successful sinus floor augmentation.
- Evaluating novel alloplasts is key to improving outcomes.
Purpose of the Study:
- To assess the regenerative capacity of a synthesized hydroxyapatite:β-tricalcium phosphate (HA:β-TCP) 60:40 alloplast.
- To determine the material's suitability for maxillary sinus augmentation.
Main Methods:
- HA:β-TCP 60:40 alloplast was used for sinus floor augmentation in 12 patients.
- Biopsies were collected after 9 months for histological analysis.
- Specimens were examined using light microscopy and digital imaging.
Main Results:
- Histological analysis revealed 26.4% newly formed bone, 27.3% residual graft, and 46.3% bone marrow.
- The calculated osteoconductive index was 33.5%.
- The material demonstrated integration and new bone formation within the augmented sinus.
Conclusions:
- The HA:β-TCP 60:40 alloplast is biocompatible for sinus augmentation.
- The material exhibits osteoconductive properties, supporting bone regeneration.
- This synthetic graft shows promise for enhancing sinus lift procedures.
