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An Injectable and Drug-loaded Supramolecular Hydrogel for Local Catheter Injection into the Pig Heart
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An Injectable and Drug-loaded Supramolecular Hydrogel for Local Catheter Injection into the Pig Heart

Published on: June 7, 2015

Supramolecular polymeric hydrogels.

Eric A Appel1, Jesús del Barrio, Xian Jun Loh

  • 1Melville Laboratory for Polymer Synthesis, Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge, UK.

Chemical Society Reviews
|August 15, 2012
PubMed
Summary
This summary is machine-generated.

Novel supramolecular polymeric hydrogels are created using dynamic non-covalent interactions in water. These advanced soft materials offer stimuli-responsiveness and self-healing for diverse applications.

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Last Updated: May 19, 2026

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Area of Science:

  • Polymer Chemistry
  • Materials Science
  • Supramolecular Chemistry

Background:

  • Supramolecular crosslinking of polymer chains in water via specific, directional, and dynamic non-covalent interactions.
  • Development of novel supramolecular polymeric hydrogels as a class of soft materials.

Purpose of the Study:

  • To critically review the formation of dynamic polymeric networks using specific non-covalent interactions.
  • To emphasize hydrogel systems based on host-guest complex formation.
  • To cover the characterization of the physical properties of these hydrogels.

Main Methods:

  • Review of literature on supramolecular chemistry and hydrogel formation.
  • Focus on host-guest complexation for network formation.
  • Analysis of characterization techniques for physical properties.

Main Results:

  • Supramolecular polymeric hydrogels exhibit stimuli-responsiveness and self-healing properties due to dynamic behavior.
  • Host-guest complexation is a key strategy for designing these dynamic networks.
  • Aqueous supramolecular chemistry provides a versatile approach for material property tuning.

Conclusions:

  • Dynamic polymeric networks formed via supramolecular interactions are crucial for advanced soft materials.
  • These hydrogels hold significant potential for various emerging applications.
  • Aqueous supramolecular chemistry offers a powerful platform for designing and tailoring hydrogel properties.