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Clinical Applications of Epidermal Stem Cells01:19

Clinical Applications of Epidermal Stem Cells

Epidermal stem cells (EpiSCs) are mainly located at the basal layer of the epidermis. These cells repair minor injuries of the skin and replace dead skin cells. However, EpiSCs’ cannot heal severe wounds such as major burns or those from diabetes or hereditary disorders. In such cases, culturing the epidermal stem cells from the patient is possible and has yielded successful treatment options, such as laboratory-grown skin grafts. These grafts are synthesized using a patient’s own EpiSCs...
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Skin Cancer

Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
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Skin Diseases and Disorders

Skin is the first line of defense and encounters a variety of microbes. Some pathogenic strains are often the cause of a broad range of infections of the skin and other body systems. These conditions can affect people of all ages and may have different causes, including genetic factors, infections, autoimmune reactions, environmental factors, and lifestyle choices.
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Transdermal drug delivery systems (TDDS) enable the controlled release of drugs across the skin into systemic circulation. They are particularly advantageous for drugs with short half-lives or narrow therapeutic indices, as they maintain consistent plasma concentrations and reduce the risk of subtherapeutic or toxic levels.TDDS are categorized into monolithic, reservoir, and mixed systems. Monolithic systems embed the drug in a polymer matrix, where diffusion governs release. Reservoir systems...
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Reticular Dermis

The papillary and reticular dermis are the two layers of the dermis. They are made of connective tissue with fibers of collagen extending from one to the other, making the border between the two somewhat indistinct. The dermal papillae extending into the epidermis belong to the papillary layer, whereas the dense collagen fiber bundles below belong to the reticular layer.
Reticular Layer
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Papillary Dermis

Dermis
The dermis might be considered the "core" of the integumentary system, as distinct from the epidermis and hypodermis. It contains blood and lymph vessels, nerves, and other structures, such as hair follicles and sweat glands. The dermis is made of two layers of connective tissue that comprise an interconnected mesh of elastin and collagenous fibers, produced by fibroblasts.
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Mobile applications for dermatology.

Michael Deveau1, Suneel Chilukuri

  • 1Baylor College of Medicine, Houston, TX, USA.

Seminars in Cutaneous Medicine and Surgery
|August 30, 2012
PubMed
Summary

The number of mobile apps has surged, making it hard to find dermatology tools. This summary aids dermatologists in selecting valuable mobile applications for their practice.

Area of Science:

  • Dermatology
  • Mobile Health (mHealth)
  • Medical Informatics

Background:

  • The proliferation of mobile applications presents a significant challenge for healthcare professionals seeking specialized tools.
  • Dermatology, in particular, has seen a rapid increase in app development, leading to an overwhelming selection.
  • Identifying high-quality, relevant applications is crucial for efficient clinical practice.

Purpose of the Study:

  • To provide a curated summary of useful mobile applications for dermatologists.
  • To assist both experienced and novice dermatologists in navigating the growing landscape of dermatology-related apps.
  • To streamline the selection process for essential mobile health tools in dermatology.

Main Methods:

  • A comprehensive review of available mobile applications relevant to dermatology was conducted.

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  • Applications were evaluated based on criteria such as clinical utility, evidence base, and user interface.
  • A selection of the most beneficial applications was compiled for this summary.
  • Main Results:

    • A significant increase in the number of mobile applications has been observed over the past three years.
    • The current market offers a wide array of dermatology applications, ranging in complexity and function.
    • Key applications offering diagnostic support, patient education, and practice management tools have been identified.

    Conclusions:

    • Selecting appropriate mobile applications can enhance dermatological practice and patient care.
    • This summary serves as a guide for dermatologists to efficiently choose valuable mHealth tools.
    • Further evaluation of emerging applications is recommended to keep pace with technological advancements.