Related Experiment Video
Updated: May 18, 2026

Microfluidic Approach to Resolve Simultaneous and Sequential Cytokine Secretion of Individual Polyfunctional Cells
Published on: March 8, 2024
Lymph and blood cytokines in fever of different severity
F I Mukhutdinova1, I G Mustafin, R Kh Khafiz'yanova
1Department of Pathophysiology, Kazan State Medical University, Russia. fimka54@mail.ru
Abstract:
Experiments on rats showed that pyrogenal-induced fever is associated with elevation of IL-1β, IL-6, and IL-10 content in the thoracic duct lymph and blood plasma, whereas low-grade fever induced by administration of Freund's complete adjuvant is associated with elevation of only IL-6 concentration. The increase in IL-1β concentration during fever and IL-6 concentration in both processes was more pronounced in the central lymph than in blood plasma. Unchanged concentrations of IL-1β and IL-10 in low-grade fever apparently reflect differences in the mechanisms of these pathological processes.
More Related Videos
Related Concept Videos
Acute Inflammation III: Local and Systemic Effects
Types of Fever
Here are the different types of fever:
Patterns of Fever
Methods of reducing fever
Pharmacological Methods of Reducing Fever:
Increased Body Temperature
Inflammatory Response I: Vascular and Cellular

