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Related Concept Videos

Sample Handling01:02

Sample Handling

Transportation of samples from the collection point to the laboratory, as well as storage and preservation techniques, are crucial for maintaining sample integrity and ensuring accurate and reliable test results.
Samples should be transported carefully from collection points to the laboratory. They should be properly sealed and clearly labeled to prevent cross-contamination. To preserve the sample integrity, optimal temperature conditions during transport are essential. This could involve using...
Microbial Classification System01:24

Microbial Classification System

Classification is the process of organizing organisms into hierarchically inclusive groups based on their phenotypic similarities or evolutionary relationships. A species comprises one or more strains, and closely related species are grouped into genera. Genera are further classified into families, families into orders, orders into classes, and so forth, up to the domain level, which is the broadest taxonomic rank derived from a combination of phenotypic and genotypic data.The nomenclature of...
Fixation and Sectioning01:03

Fixation and Sectioning

Two basic types of preparation are used to visualize specimens with a light microscope: wet mounts and fixed specimens.
The simplest type of preparation is the wet mount, in which the specimen is placed in a drop of liquid on the slide. A liquid specimen can be directly deposited on the slide using a dropper. Solid specimens, such as skin scraping, can be placed on the slide before adding a drop of liquid to prepare the wet mount. Sometimes the liquid is simply water, but stains are often added...

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Updated: May 18, 2026

Biobank for Translational Medicine: Standard Operating Procedures for Optimal Sample Management
08:01

Biobank for Translational Medicine: Standard Operating Procedures for Optimal Sample Management

Published on: November 30, 2022

Biological sample collection, processing, storage and information management.

Jimmie B Vaught1, Marianne K Henderson

  • 1National Cancer Institute, Bethesda, MD, USA. vaughtj@mail.nih.gov

IARC Scientific Publications
|September 25, 2012
PubMed
Summary
This summary is machine-generated.

Biological resource centres manage crucial biological samples for research. Proper collection, processing, and storage protocols are essential for ensuring sample quality and reliable study outcomes.

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Area of Science:

  • Biorepository science
  • Sample management
  • Biospecimen research

Background:

  • Biological resource centres (BRCs) are vital repositories for biological samples and associated data.
  • Effective management of biospecimens is complex and often underestimated.
  • Decisions made during sample collection, processing, and storage significantly impact research quality.

Purpose of the Study:

  • To highlight the complexities and critical considerations in biological sample management within BRCs.
  • To emphasize the importance of standardized protocols for sample integrity.
  • To underscore the necessity of robust quality management systems in biospecimen resources.

Main Methods:

  • Selection of appropriate sample types for specific research needs.
  • Implementation of suitable processing protocols to ensure sample quality.
  • Establishment of proper storage conditions to maintain sample integrity until analysis.
  • Utilization of sample tracking and laboratory informatics systems for monitoring and control.

Main Results:

  • Underestimation of complexities in sample management policies and procedures is common.
  • Inadequate attention to sample type, processing, and storage can compromise study outcomes.
  • Effective sample management requires careful planning and execution.

Conclusions:

  • A comprehensive quality management system with standard operating procedures is essential for BRCs.
  • Consistent sample quality is critical for reliable laboratory analyses and achieving study goals.
  • Adherence to best practices in biospecimen resource management ensures research validity.