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Published on: April 29, 2013
Capillaroscopy and ECG parameters in children and adolescents with diabetes mellitus type I
Insights
This study found that electrocardiogram (ECG) and capillaroscopy reveal early changes in children with type 1 diabetes (DMT1). Regular monitoring of these parameters is crucial for timely intervention and treatment.
Area of Science:
- Pediatric Endocrinology
- Cardiology
- Diabetology
Background:
- Type 1 diabetes (DMT1) can lead to cardiac and vascular complications in children and adolescents.
- Early detection of these complications is essential for effective management.
Purpose of the Study:
- To evaluate electrocardiogram (ECG) parameters and capillaroscopy findings in pediatric patients with DMT1.
- To identify early signs of cardiac involvement and microvascular changes associated with DMT1.
Main Methods:
- ECG and capillaroscopy were performed on 32 children and adolescents with DMT1 and 20 healthy controls.
- Patients were categorized based on disease duration and presence of complications, including cardiac, neurological, and renal issues.
- Blood glucose and glycosylated hemoglobin levels were monitored.
Main Results:
- Group II (with cardiac complications) showed higher prevalence of left ventricular/atrial hypertrophy and repolarization disorders compared to Group I (no complications).
- Rhythm and conduction abnormalities were observed in 62.5% of DMT1 patients, more frequently in Group II.
- Capillaroscopy revealed significant changes in both groups, with greater intensity and prevalence in patients with complications.
Conclusions:
- ECG and capillaroscopy are valuable tools for detecting early subclinical changes in pediatric patients with DMT1.
- Regular screening using these methods can facilitate timely diagnosis and treatment of diabetes-related complications.
Aim Of The Research:
Evaluate ECG parameters and detect changes in capillaroscopy parameters in children and adolescents with Diabetes mellitus type 1 (DMT1). ECG and capillaroscopy were performed in 32 children and adolescents (6-15 years old, 17 boys,15 girls) with DMT1. Disease duration - less than 2 years -13, 2-4 years - 10, 5-10 years - 9 cases. The patients were divided into two groups: I group - 12 patients with no complications of DMT1 (in all them duration of disease was less than 2 years), II group - 20 patients with diagnosed cardiac complications of DMT1 (diabetic cardiomyopathy, angiopathy). Additionally 6 of them had diabetic encephalopathy , 4 - diabetic encephalopathy and peripheral neuropathy, 4 - nephropathy and retinal antipathy. Level of glycosides hemoglobin was 8-11%, level of glucose 4 to 15 mmole/L. Control group included 20 healthy children of the same age. In group I ECG is less informative. Hypertrophies of left ventricle and atrium and disorders of repolarization were mainly found in group II. In 62.5% of cases rhythm and conduction disorders were revealed, which were more often in group II. Capillaroscopy changes (pale and cyanotic background, decreasing of the number of capillaries in sight, dilated and contracted diameter, pathological shape and order of capillaries, slow blood flow) were seen both in I and II groups with more prevalence and intensity in the latter one. In children and adolescents with Diabetes mellitus type 1 ECG and capillaroscopy should be performed on the regular basis in order to reveal early changes and start the appropriate treatment in time.
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