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Multifocal photodynamic therapy for diffuse choroidal hemangioma.
1Singapore Eye Research Institute, Singapore National Eye Centre, Singapore.
Clinical Ophthalmology (Auckland, N.Z.)
|October 12, 2012
Summary
Diffuse choroidal hemangiomas in Asian patients, like this case of Sturge-Weber syndrome, often need multiple photodynamic therapy (PDT) sessions for effective treatment and resolution of subretinal fluid.
Area of Science:
- Ophthalmology
- Vascular Oncology
Background:
- Choroidal hemangiomas are rare benign vascular tumors.
- Diffuse forms, particularly in Asian patients, present unique treatment challenges.
Observation:
- A 7-year-old boy with Sturge-Weber syndrome presented with a diffuse choroidal hemangioma.
- Five photodynamic therapy (PDT) sessions were administered over one year.
Findings:
- Initial PDT sessions were insufficient for complete tumor destruction.
- Recurrent subretinal fluid, not tumor size, guided the decision for repeat treatments.
- Final visual acuity was 20/100 with resolved subretinal fluid and hemangioma.
Implications:
- Larger, dilated vessels in choroidal hemangiomas may reduce PDT efficacy in Asian patients.
- Multiple PDT sessions may be necessary for optimal outcomes in this demographic.
- This case highlights the need for tailored PDT protocols for diffuse choroidal hemangiomas.
