Related Experiment Video
Updated: May 17, 2026

Human Subcutaneous Adipose Tissue Sampling Using a Mini-Liposuction Technique
Published on: September 27, 2021
Safety of liver biopsy as a day procedure in Abuth Zaria, Nigeria
David Olorunfemi Samuel1, Ibinaiye Philip Oluleke, Samaila Modupeola Omotara
1Department of Medicine, Ahmadu Bello University Teaching Hospital, Zaria, Nigeria. daves074ds@yahoo.com
Insights
Liver biopsy is a key diagnostic tool for chronic liver disease (CLD). This study found post-procedure pain to be the most common side effect, with chronic viral hepatitis being the primary indication.
Area of Science:
- Hepatology
- Gastroenterology
- Medical Procedures
Background:
- Chronic liver disease (CLD) is a significant health issue and a leading cause of mortality.
- Hepatocellular carcinoma, often a consequence of CLD, has a high mortality rate, particularly in sub-Saharan Africa.
- Liver biopsy remains a primary diagnostic method for CLD.
Purpose of the Study:
- To evaluate the safety and frequency of indications for liver biopsy.
- To assess complications associated with liver biopsy procedures.
- To analyze data from liver biopsies performed between January 2000 and January 2009.
Main Methods:
- Retrospective analysis of 279 liver biopsy entries.
- Histological confirmation of liver biopsy results for 270 patients (96.77%).
- Documentation of indications, complications, and duration of hospital stay.
Main Results:
- The primary indication for liver biopsy was chronic viral hepatitis, noted in 150 patients (53.76%).
- Post-procedure pain was the most frequent complication, affecting 16 patients (5.7%).
- The average hospital stay post-biopsy was 6.08 ± 0.52 hours.
Conclusions:
- Liver biopsy is a generally safe procedure for diagnosing chronic liver disease.
- Chronic viral hepatitis is the predominant indication for liver biopsy in this cohort.
- Post-procedure pain is the most common, manageable complication of liver biopsy.
Abstract:
Chronic liver disease (CLD) is an important condition, diagnosed mainly by liver biopsy and is a leading cause of death among the working class group. It is a major burden in sub-Saharan Africa where it leads to hepatocellular carcinoma with a high mortality. This study was a retrospective one undertaken to determine the safety of performing liver biopsy procedure between January 2000 to January 2009 in terms of the frequency of indications and side effects. A total of 279 entries were found out of which 270 (96.77%) had a definitive liver biopsy histology result. The main indication for liver biopsy was chronic viral hepatitis in 150 patients (53.76%) while the commonest complication was the post-procedure pain that was seen in 16 patients (5.7%). The average duration of hospital stay after biopsy was 6.08 ± 0.52 hours.
