Safety of liver biopsy as a day procedure in Abuth Zaria, Nigeria

David Olorunfemi Samuel1, Ibinaiye Philip Oluleke, Samaila Modupeola Omotara

  • 1Department of Medicine, Ahmadu Bello University Teaching Hospital, Zaria, Nigeria. daves074ds@yahoo.com

Insights

Liver biopsy is a key diagnostic tool for chronic liver disease (CLD). This study found post-procedure pain to be the most common side effect, with chronic viral hepatitis being the primary indication.

Area of Science:

  • Hepatology
  • Gastroenterology
  • Medical Procedures

Background:

  • Chronic liver disease (CLD) is a significant health issue and a leading cause of mortality.
  • Hepatocellular carcinoma, often a consequence of CLD, has a high mortality rate, particularly in sub-Saharan Africa.
  • Liver biopsy remains a primary diagnostic method for CLD.

Purpose of the Study:

  • To evaluate the safety and frequency of indications for liver biopsy.
  • To assess complications associated with liver biopsy procedures.
  • To analyze data from liver biopsies performed between January 2000 and January 2009.

Main Methods:

  • Retrospective analysis of 279 liver biopsy entries.
  • Histological confirmation of liver biopsy results for 270 patients (96.77%).
  • Documentation of indications, complications, and duration of hospital stay.

Main Results:

  • The primary indication for liver biopsy was chronic viral hepatitis, noted in 150 patients (53.76%).
  • Post-procedure pain was the most frequent complication, affecting 16 patients (5.7%).
  • The average hospital stay post-biopsy was 6.08 ± 0.52 hours.

Conclusions:

  • Liver biopsy is a generally safe procedure for diagnosing chronic liver disease.
  • Chronic viral hepatitis is the predominant indication for liver biopsy in this cohort.
  • Post-procedure pain is the most common, manageable complication of liver biopsy.

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