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[Onychomycosis : a crown jewel of dermatology]
1Institut für Pilzkrankheiten, Luisenstr. 50, 10117, Berlin, Deutschland. tietz@institut-fuer-pilzkrankheiten.de
Abstract:
Onychomycosis is a curable infection disease. It is widespread, but not easy to treat. Because fungal pathogens never induce immunity, the relapse rate of mycoses is generally high. The main causes are residual fungal spores in the nail and the individual susceptibility of the patient, which can hardly be influenced. Crucial for long-term therapeutic success is a sporicidal topical therapy. In severe cases ones also needs long-term, well-tolerated systemic therapy, based on accurate microbiological diagnosis of the causative agent. Presented is a three-step therapeutic approach that is easy to perform, well- tolerated and produces sustained results.
Insights
Onychomycosis, a fungal nail infection, is treatable but prone to relapse due to persistent spores and patient susceptibility. A sporicidal topical therapy combined with systemic treatment and accurate diagnosis is key for sustained results.
Area of Science:
- Dermatology
- Mycology
- Infectious Diseases
Context:
- Onychomycosis is a prevalent fungal infection impacting nail health.
- High relapse rates are common due to residual fungal spores and individual susceptibility.
- Effective treatment requires addressing both the infection and underlying factors.
Purpose:
- To present a novel three-step therapeutic approach for managing onychomycosis.
- To outline a treatment strategy that is easy to implement and well-tolerated.
- To achieve sustained therapeutic success in treating fungal nail infections.
Summary:
- The study details a three-step treatment plan for onychomycosis.
- This approach emphasizes sporicidal topical therapy as crucial for long-term success.
- In severe cases, long-term, well-tolerated systemic therapy, guided by microbiological diagnosis, is recommended.
Impact:
- Provides a practical and effective strategy for clinicians treating onychomycosis.
- Aims to reduce the high relapse rates associated with fungal nail infections.
- Offers a well-tolerated treatment option for patients, improving long-term outcomes.
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