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Updated: May 17, 2026

Induction of Cerebral Arterial Gas Embolism in Rat
Published on: October 18, 2024
[Retrograde cavernous sinus air embolism after central venous catheter removal]
Takumi Yamanaka1, Yuko Miyazaki, Masaharu Sato
1Department of Neurosurgery, Toyonaka Municipal Hospital, Takatsuki-City, Osaka, Japan.
Abstract:
Air embolism is a rare, but occasionally fatal complication of peripheral and central venous catheterization. We present a case of an 89-year-old female, who had a central venous catheter placed in her right jugular vein during the perioperative period for right femoral subtrochanteric fracture. On the day following her operation, level of consciousness worsened a few minutes after the catheter was removed. CT scan showed air bubbles in bilateral cavernous sinuses and brachiocephalic vein. Administration of 100% oxygen was started, and she regained consciousness a few hours later, finally air bubbles disappeared on a CT scan performed 10 hours after onset. Air embolism should be taken into consideration when treating venous catheters, and appropriate O₂ administration and radiological examinations must be performed immediately if level of consciousness or vital signs deteriorate.
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