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Published on: July 23, 2016
Frequency and management of raised intraocular pressure following intravitreal triamcinolone acetonide
Pir Salim Mahar1, Abdul Sami Memon
1Department of Ophthalmology, Isra Postgraduate Institute of Ophthalmology, Al-Ibrahim Eye Hospital, Malir, Karachi. salim.mahar@aku.edu
Objective:
To determine the frequency and management of intraocular pressure (IOP) elevation following intravitreal triamcinolone acetonide (IVTA).
Study Design:
Case series.
Place And Duration Of Study:
Isra Postgraduate Institute of Ophthalmology/Al-Ibrahim Eye Hospital, Karachi, from May 2007 to May 2008.
Methodology:
In this study, 198 eyes of 150 patients requiring IVTA injection, were included. Pre-injection assessment comprised of detailed history, general and ocular examination including anterior and posterior segment examination with IOP measurements with Goldmann tonometer. After informed consent, IVTA 4 mg/0.1 ml was injected through pars plana and IOP was measured at 1 week, 1 month, 3 months and 6 months and if raised, treated accordingly.
Results:
Out of 150 patients, 82 were male (54.7%) and 68 were female (45.3%) (M: F = 1.2: 1). Mean age was 50.61 ± 10.59 years. Raised IOP value after IVTA, higher than 21 mmHg was observed at one week in 28 eyes (14.1%), at 1 month n 48 eyes (24.2%), at 3 months in 76 eyes (38.4%) and at 6 months in 25 eyes (12.6%). Raised IOP was controlled by topical beta blockers alone or in combination with carbonic anhydrase inhibitors in 58 eyes (76.3%).
Conclusion:
Elevation of IOP after IVTA injection occurred in 76 eyes (38.3%). It may take an extended period of time to manifest raised IOP. In majority of the patients, raised IOP was managed with topical medications.
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