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Updated: May 16, 2026

A Rat Model of Pouchitis Following Proctocolectomy and Ileal Pouch-Anal Anastomosis Using Dextran Sulfate Sodium
Published on: May 31, 2024
Considerations and complications in patients undergoing ileal pouch anal anastomosis
Todd D Francone1, Brad Champagne
1Department of Colon and Rectal Surgery, University of Rochester Medical Center, Rochester, NY 14642, USA. todd_francone@urmc.rochester.edu
Abstract:
Total proctocolectomy with ileal pouch anal anastomosis (IPAA) preserves fecal continence as an alternative to permanent end ileostomy in select patients with ulcerative colitis and familial adenomatous polyposis. The procedure is technically demanding, and surgical complications may arise. This article outlines both the early and late complications that can occur after IPAA, as well as the workup and management of these potentially morbid conditions.
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