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Related Concept Videos

Pharmacokinetics in Pediatric Patients: Overview and Drug Absorption01:23

Pharmacokinetics in Pediatric Patients: Overview and Drug Absorption

Understanding the physiological differences in the pediatric population is crucial for effective pharmacotherapy. Neonates, infants, and children exhibit significant variations in gastric pH, gastric emptying time, intestinal transit time, and biliary function. These variations profoundly affect oral drug absorption, necessitating a nuanced approach to pediatric dosing.Neonates present with a unique physiological profile, having a gastric pH greater than 4 and faster and more irregular gastric...
Assessment of the Rectum and Anus01:25

Assessment of the Rectum and Anus

Evaluating the rectum and anus plays a crucial role in conducting a thorough physical examination of the gastrointestinal system. Although it may be uncomfortable and often embarrassing for the patient, it holds immense diagnostic value, particularly in detecting gastrointestinal diseases and abnormalities. This guide will explain how to perform this assessment using inspection and palpation methods.
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Endoscopic Procedures II: Colonoscopy01:25

Endoscopic Procedures II: Colonoscopy

The colon, or large intestine, is the final segment of the digestive system. Its primary functions include absorbing water and vitamins produced by gut bacteria and transforming waste from liquid to solid to form stool. In adults, the large intestine is approximately 5 feet long and consists of four main sections:
Pharmacokinetics in Pediatric Patients: Drug Excretion01:26

Pharmacokinetics in Pediatric Patients: Drug Excretion

In pediatric medicine, understanding the renal function and drug elimination nuances is crucial for administering safe and effective treatments. Newborns, in particular, display markedly slower renal functions than adults, profoundly affecting how drugs are cleared from their bodies. This slower drug clearance requires clinicians to extend the dosing intervals for many medications to prevent drug accumulation and toxicity while ensuring therapeutic efficacy.One key area where these adjustments...
Lower GI Series: Barium Enema01:23

Lower GI Series: Barium Enema

A Barium Enema, or a lower GI series, is a specialized radiographic examination designed to visualize the lower gastrointestinal tract, specifically the colon and rectum. This procedure is instrumental in diagnosing various conditions such as colorectal cancer, polyps, diverticulosis, and inflammatory bowel disease.
Procedure Details
The examination begins by inserting a lubricated rectal tube into the patient's rectum to administer a radiopaque barium solution. The barium flow is carefully...
Drug Dosing: Infants and Children01:29

Drug Dosing: Infants and Children

Pediatric patient dosages diverge from adults due to disparities in body surface area, total body water, and extracellular fluid per kilogram of body weight. The dosing regimen considers the variations in pharmacokinetics and pharmacology across distinct age groups, encompassing preterm newborns, infants, young children, older children, and adolescents. Calculation of pediatric patient doses is predicated on determining body surface area, which exhibits a superior correlation with the child's...

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Competing-Risk Nomogram for Predicting Cancer-Specific Survival in Multiple Primary Colorectal Cancer Patients after Surgery
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Published on: September 27, 2024

Colorectal considerations in pediatric patients.

David M Gourlay1

  • 1Division of Pediatric Surgery, Department of Surgery, Medical College of Wisconsin, Milwaukee, WI 53226, USA. dgourlay@chw.org

The Surgical Clinics of North America
|November 27, 2012
PubMed
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Pediatric colorectal diseases significantly impact quality of life, often requiring lifelong care. This article focuses on conditions more prevalent in children, distinct from adult management strategies.

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Area of Science:

  • Pediatric Gastroenterology
  • Colorectal Surgery
  • Pediatric Oncology

Background:

  • Colorectal diseases in children present unique challenges.
  • Many pediatric colorectal conditions necessitate long-term management extending into adulthood.
  • Understanding disease-specific pediatric presentations is crucial for effective care.

Purpose of the Study:

  • To highlight colorectal diseases more common in pediatric populations.
  • To differentiate pediatric colorectal disease management from adult protocols.
  • To provide a focused overview of pediatric-specific colorectal conditions.

Main Methods:

  • Literature review of pediatric colorectal disease.
  • Comparative analysis of pediatric versus adult management.
  • Identification of prevalent pediatric colorectal conditions.

Main Results:

  • Pediatric colorectal diseases encompass a wide range of conditions.
  • Some pediatric colorectal diseases mirror adult disease management (e.g., IBD, colon cancer).
  • Several colorectal conditions are distinctly more common in children.

Conclusions:

  • Effective management of pediatric colorectal disease requires specialized knowledge.
  • Long-term follow-up is essential for pediatric patients with colorectal conditions.
  • This article emphasizes pediatric-specific colorectal disease processes.