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Updated: May 15, 2026

A Simplified Stepwise Approach to Echo Guidance during Percutaneous Mitral Valve Repair
Published on: October 16, 2021
Percutaneous paravalvular leak closure- imaging, techniques and outcomes.
Amar Krishnaswamy1, Samir R Kapadia, E Murat Tuzcu
1Cardiovascular Medicine, Cleveland Clinic, Cleveland, OH 44195, USA. krishna2@ccf.org
Paravalvular leak (PVL) closure via percutaneous methods offers a promising alternative to surgery. This review details imaging and procedural techniques for PVL closure, highlighting successful clinical outcomes.
Area of Science:
- Cardiology
- Interventional Cardiology
- Medical Imaging
Background:
- Paravalvular leak (PVL) is a complication of valve replacement.
- Surgical PVL repair has high risks and lower success rates.
- Percutaneous PVL closure is an emerging alternative.
Purpose of the Study:
- To review imaging and procedural techniques for percutaneous PVL closure.
- To present data supporting percutaneous PVL closure as a treatment strategy.
Main Methods:
- Comprehensive review of existing literature.
- Emphasis on multimodality imaging for diagnosis and guidance.
- Focus on percutaneous closure techniques in the cardiac catheterization laboratory.
Main Results:
- Several large series of percutaneous PVL closure have been published.
- Encouraging results reported for procedural success.
- Positive clinical outcomes demonstrated for percutaneous PVL closure.
Conclusions:
- Percutaneous PVL closure is a viable and effective treatment option.
- Multimodality imaging is crucial for successful PVL closure.
- This approach offers improved outcomes compared to repeat surgery.
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