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Automated 90Sr Separation and Preconcentration in a Lab-on-Valve System at Ppq Level
Published on: June 6, 2018
Determination of 90Sr-90Y activity in urine samples by using Cherenkov counting
Summary
Cherenkov counting is effective for measuring Strontium-90/Yttrium-90 in urine. The External Source Area Ratio (ESAR) method accurately corrects for color quenching in these samples.
Area of Science:
- Nuclear Chemistry
- Radiochemistry
- Analytical Chemistry
Background:
- Cherenkov counting is a viable technique for quantifying pure beta emitters like Strontium-90/Yttrium-90 in aqueous samples.
- Urine samples often exhibit significant color, leading to quenching that complicates accurate radioactivity measurements.
- Effective quench correction is crucial for reliable results in radiochemical analysis of biological samples.
Purpose of the Study:
- To evaluate the applicability of the External Source Area Ratio (ESAR) method for quench correction in Cherenkov counting.
- To determine Strontium-90/Yttrium-90 concentrations in human urine samples using Cherenkov counting with ESAR correction.
Main Methods:
- Utilized Cherenkov counting for the detection of beta emissions from Strontium-90/Yttrium-90.
- Applied the External Source Area Ratio (ESAR) method, a technique employing an external source for quench correction.
- Analyzed human urine samples to assess the practical performance of the ESAR method in complex matrices.
Main Results:
- The ESAR method demonstrated effectiveness in correcting for color quenching in aqueous solutions.
- Successful application of the ESAR method allowed for the determination of Strontium-90/Yttrium-90 in colored human urine samples.
- The study confirmed the feasibility of using Cherenkov counting with ESAR for routine analysis.
Conclusions:
- The ESAR method is a suitable approach for quench correction in Cherenkov counting of Strontium-90/Yttrium-90 in human urine.
- This method enhances the accuracy and reliability of radioactivity measurements in complex, colored biological samples.
- Cherenkov counting combined with ESAR offers a practical solution for monitoring Strontium-90/Yttrium-90 in environmental and biomedical contexts.
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