Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Bias01:22

Bias

Bias refers to any tendency that prevents a question from being considered unprejudiced. In research, bias occurs when one outcome or answer is selected or encouraged over others in sampling or testing. Bias can occur during any research phase, including study design, data collection, analysis, and publication.
In statistics, a sampling bias is created when a sample is collected from a population, and some members of the population are not as likely to be chosen as others (remember, each member...
Functional Brain Systems: Limbic System01:15

Functional Brain Systems: Limbic System

The limbic system, often called the "emotional brain," is a complex set of structures located deep within the brain. The intricate network of the limbic system supports a wide range of psychological functions, from emotional regulation to memory formation and sensory processing. This functional brain region encompasses specific parts of the diencephalon and the cerebrum, integrating the higher mental functions of the cerebral cortex with the primitive emotional responses of the deep brain...
Reason and Intuition01:37

Reason and Intuition

The human brain processes information for decision-making using one of two routes: an intuitive system and a rational system (Epstein, 1994; popularized by Kahneman, 2011 as System 1 and System 2, respectively). The intuitive system is quick, impulsive, and operates with minimal effort, relying on emotions or habits to provide cues for what to do next, while the rational system is logical, analytical, deliberate, and methodical. Research in neuropsychology suggests that the brain can only use...
Organization of the Brain01:30

Organization of the Brain

The brain is an integral component of the nervous system and serves as the center for processing sensory inputs, making decisions, and directing bodily actions. This complex organ is organized into three primary sections: the hindbrain, midbrain, and forebrain, each responsible for a range of vital functions.
Hindbrain
The hindbrain, located at the base of the brain, plays a vital role in regulating automatic processes that sustain life. It includes the medulla oblongata, which is essential for...
Gut-Brain Axis01:22

Gut-Brain Axis

The gut–brain axis is a bidirectional communication system that connects the gastrointestinal tract and the brain. This interaction is mediated through multiple pathways, including the vagus nerve, hormonal signals, immune responses, and chemical messengers produced by gut microbes.Microbial Contributions to Brain FunctionGut microbiota contributes significantly to brain function by producing neuroactive compounds. These include neuroactive compounds that influence neurotransmitters such as...
Diagnostic and Statistical Manual of Mental Disorders (DSM)01:27

Diagnostic and Statistical Manual of Mental Disorders (DSM)

The Diagnostic and Statistical Manual of Mental Disorders (DSM) serves as the primary classification system for mental health disorders, providing standardized diagnostic criteria for clinicians and researchers. First published by the American Psychiatric Association (APA) in 1952, the DSM has undergone several revisions to reflect evolving psychiatric understanding. The fifth edition, DSM-5, released in 2013, introduced key updates that expanded diagnostic categories and modified diagnostic...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Before Diagnostic Closure: State-Forming Information in Psychiatric Assessment.

Psychotherapy and psychosomatics·2026
Same author

Identification of autoantibodies against L1CAM in patients with schizophrenia.

Brain, behavior, & immunity - health·2026
Same author

An integrative NLP framework identifies multilevel linguistic phenotypes of schizophrenia across tasks.

Psychological medicine·2026
Same author

Factors Influencing Treatment Dropout Among Child and Adolescent Psychiatric Patients: A Survival Analysis.

Journal of clinical psychology in medical settings·2026
Same author

Striatal DAT-SPECT texture beyond mean binding in major depressive disorder.

Journal of affective disorders·2026
Same author

Grit mediates social success across attention deficit/hyperactivity disorder tendencies.

Acta psychologica·2026
Same journal

[Neuropathological Autopsies in Japan: Current Scenario and Challenges].

Brain and nerve = Shinkei kenkyu no shinpo·2026
Same journal

[Telemedicine and Digital Technologies in Neurological Intractable Diseases].

Brain and nerve = Shinkei kenkyu no shinpo·2026
Same journal

[Disaster Countermeasures for Intractable Neurological Disease].

Brain and nerve = Shinkei kenkyu no shinpo·2026
Same journal

[Supporting Health Care Transition for Patients with Childhood-Onset Chronic Conditions: Within Intractable Disease Care in Japan].

Brain and nerve = Shinkei kenkyu no shinpo·2026
Same journal

[Multidisciplinary Collaboration between Hospitals and Clinics at the University Hospital and the Core Hospital for the Treatment of Intractable Diseases].

Brain and nerve = Shinkei kenkyu no shinpo·2026
Same journal

[The Role of Coordinators for Intractable Diseases in Japan].

Brain and nerve = Shinkei kenkyu no shinpo·2026
See all related articles

Related Experiment Video

Updated: May 15, 2026

Transcranial Direct Current Stimulation for Online Gamers
06:01

Transcranial Direct Current Stimulation for Online Gamers

Published on: November 9, 2019

[Gambling brain].

Kosuke Tsurumi1, Hidehiko Takahashi

  • 1Department of Psychiatry, Graduate School of Medicine Kyoto University, Japan.

Brain and Nerve = Shinkei Kenkyu No Shinpo
|January 10, 2013
PubMed
Summary
This summary is machine-generated.

Pathological gambling (PG) is a chronic mental disorder characterized by an inability to stop gambling. Neuroimaging studies reveal reduced sensitivity to rewards and losses, heightened cue reactivity, and increased impulsivity in PG patients.

More Related Videos

The Joint Effect of Social Comparison and Social Distance on Evaluation of Intertemporal Choice Outcomes in Event-related Potential Studies
08:24

The Joint Effect of Social Comparison and Social Distance on Evaluation of Intertemporal Choice Outcomes in Event-related Potential Studies

Published on: August 25, 2023

Measuring the Subjective Value of Risky and Ambiguous Options using Experimental Economics and Functional MRI Methods
13:04

Measuring the Subjective Value of Risky and Ambiguous Options using Experimental Economics and Functional MRI Methods

Published on: September 19, 2012

Related Experiment Videos

Last Updated: May 15, 2026

Transcranial Direct Current Stimulation for Online Gamers
06:01

Transcranial Direct Current Stimulation for Online Gamers

Published on: November 9, 2019

The Joint Effect of Social Comparison and Social Distance on Evaluation of Intertemporal Choice Outcomes in Event-related Potential Studies
08:24

The Joint Effect of Social Comparison and Social Distance on Evaluation of Intertemporal Choice Outcomes in Event-related Potential Studies

Published on: August 25, 2023

Measuring the Subjective Value of Risky and Ambiguous Options using Experimental Economics and Functional MRI Methods
13:04

Measuring the Subjective Value of Risky and Ambiguous Options using Experimental Economics and Functional MRI Methods

Published on: September 19, 2012

Area of Science:

  • Neuroscience
  • Psychiatry
  • Behavioral Science

Context:

  • Pathological gambling (PG) is a chronic mental disorder often misunderstood as a lack of willpower.
  • Evidence suggests PG shares similarities with substance use disorders, prompting its proposed reclassification in DSM-5.
  • PG prevalence may be higher in Japan compared to Western countries, yet it receives limited attention.

Purpose:

  • To review neuroimaging studies on pathological gambling.
  • To analyze findings across four key dimensions: reward/loss sensitivity, craving/cue reactivity, impulsivity, and decision-making.
  • To explore the potential of molecular neuroimaging and neuroeconomics in understanding PG.

Summary:

  • Neuroimaging studies indicate that individuals with PG exhibit diminished sensitivity to monetary rewards and losses.
  • Patients with PG demonstrate increased reactivity to gambling-related cues and heightened impulsivity.
  • Decision-making in PG is complex; future research should dissect its individual components.

Impact:

  • Understanding the neurobiological underpinnings of PG can aid in developing effective assessment and prevention strategies.
  • Insights into altered decision-making mechanisms may inform novel pharmacological treatments for gambling addiction.
  • This research contributes to the broader understanding of addiction and related disorders.