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Fatal pyoderma gangrenosum with pathergy after coronary artery bypass grafting

Charles S Bryan1

  • 1Department of Internal Medicine, Providence Hospitals, Columbia, South Carolina 29203, USA. cboslerian@gmail.com

Texas Heart Institute Journal
|January 11, 2013
PubMed

Insights

Pyoderma gangrenosum (PG) can occur after coronary artery bypass grafting (CABG), presenting a risk of pathergy. This case highlights a fatal outcome due to PG-induced graft perforation following CABG.

Area of Science:

  • Cardiovascular Surgery
  • Dermatology
  • Pathology

Background:

  • Pyoderma gangrenosum (PG) is a rare inflammatory ulcerative skin condition.
  • Pathergy, an exaggerated inflammatory response to minor trauma, can exacerbate PG.
  • Invasive procedures carry a risk of triggering PG and pathergy in susceptible individuals.
Keywords:
Coronary artery bypass/complicationsdiagnosis, differentialfatal outcomepostoperativecomplications/diagnosis/drug therapy/pathologypyoderma gangrenosum/complications/diagnosis/etiology/pathology/therapyrisk factorsskin ulcer/diagnosisskin/injuries/pathologysurgical wound infection/diagnosiswound healing

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