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Related Concept Videos

Changes in Skin Color: Clinical Perspectives01:14

Changes in Skin Color: Clinical Perspectives

The first thing a clinician sees is the skin, so the examination of the skin should be part of any thorough physical examination. Most skin disorders are relatively benign, but a few, including melanomas, can be fatal if untreated. A couple of the more noticeable disorders, albinism and vitiligo, affect the appearance of the skin and its accessory organs.
Albinism
Albinism is a genetic disorder that affects (completely or partially) the coloring of skin, hair, and eyes. The defect is primarily...
Confocal Fluorescence Microscopy01:16

Confocal Fluorescence Microscopy

Confocal microscopy is an advanced microscopic technique. The prime advantage of the confocal microscope over other microscopy techniques is its ability to block the out-of-focus light from the illuminated samples using pinholes. It is widely used with fluorescence optics to obtain high-resolution, sharp contrast images. Unlike optical microscopes, confocal microscopes use a focused beam of light laser to scan the entire sample surface at different z-planes. These microscopes are, therefore,...
Skin Diseases and Disorders01:23

Skin Diseases and Disorders

Skin is the first line of defense and encounters a variety of microbes. Some pathogenic strains are often the cause of a broad range of infections of the skin and other body systems. These conditions can affect people of all ages and may have different causes, including genetic factors, infections, autoimmune reactions, environmental factors, and lifestyle choices.
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
Skin Cancer01:30

Skin Cancer

Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
Acne Infection01:27

Acne Infection

Acne is a multifactorial skin condition primarily affecting adolescents and young adults, with a global prevalence estimated to exceed 75% in this demographic. The condition is characterized by the formation of comedones (blackheads and whiteheads), papules, pustules, nodules, and, in severe cases, cysts, particularly in areas rich in sebaceous glands such as the face, neck, chest, and back. The pathogenesis involves increased sebum production, follicular hyperkeratinization, colonization by...
Reticular Dermis01:15

Reticular Dermis

The papillary and reticular dermis are the two layers of the dermis. They are made of connective tissue with fibers of collagen extending from one to the other, making the border between the two somewhat indistinct. The dermal papillae extending into the epidermis belong to the papillary layer, whereas the dense collagen fiber bundles below belong to the reticular layer.
Reticular Layer
Underlying the papillary layer is the much thicker reticular layer, composed of dense, irregular connective...

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Related Experiment Video

Updated: May 15, 2026

Apparatus for Harvesting Tissue Microcolumns
06:06

Apparatus for Harvesting Tissue Microcolumns

Published on: October 25, 2018

[What's new in dermatology?].

Arieh Ingber1

  • 1Department of Dermatology, Hadassah University Hospital, Faculty of Medicine, Hebrew University, Jerusalem, Israel. AINGBER7@WALLA.COM

Harefuah
|January 16, 2013
PubMed
Summary

Recent advancements in dermatology include genetic insights into skin disease classification, new understandings of disease processes, and innovative treatments. This review covers psoriasis, polyarteritis nodosa, and novel immunotherapies for melanoma.

Area of Science:

  • Dermatology
  • Genetics
  • Immunology

Context:

  • The last decade has seen significant innovations in understanding and treating skin diseases.
  • Advances are driven by genetic research, improved diagnostics, and novel therapeutic approaches.
  • Dermatology is also benefiting from technological progress, such as advanced imaging techniques.

Purpose:

  • To review recent key advances in the field of dermatology.
  • To highlight innovations in skin disease classification, understanding, diagnosis, and treatment.
  • To detail the application of in vivo reflected mode confocal laser microscopy in dermatology.

Summary:

  • This review covers advances in skin disease management, including psoriasis as a multi-system disease.
  • New insights into polyarteritis nodosa, parapsoriasis, autoinflammatory syndromes, and pustular psoriasis of pregnancy are discussed.

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Apparatus for Harvesting Tissue Microcolumns
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  • The review also addresses new immunotherapy for metastatic melanoma and the use of confocal laser microscopy.
  • Impact:

    • Provides a comprehensive overview of recent dermatological innovations.
    • Enhances understanding of complex skin conditions and their management.
    • Showcases the potential of new technologies in dermatological diagnosis and research.