[The disease burden of human papillomavirus in men is substantial and can potentially be prevented]
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Updated: May 14, 2026

RNAscope for In situ Detection of Transcriptionally Active Human Papillomavirus in Head and Neck Squamous Cell Carcinoma
Published on: March 11, 2014
Helle Kiellberg Larsen1, Kristian Kofoed, Carsten Sand
1Dermato-venerologisk Afdeling D, Bispebjerg Hospital, Bispebjerg Bakke 23, 2400 København NV, Denmark. hellekl@dadlnet.dk
Abstract:
Human papillomavirus (HPV) is a highly prevalent sexually transmitted infection. High-risk HPV causes penile cancer and a substantial proportion of oropharyngeal and anal malignancy in men. Low-risk types of HPV cause anogenital warts. The incidence of oropharyngeal and anal cancers is increasing in Denmark. Prevention of penile, anal and oropharyngeal cancers and anogenital warts represents potential benefits of the HPV vaccine; and vaccination of men is now recommended by the Australian and the North American health authorities. Thus, we recommend that the Danish HPV vaccination program should include men.
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