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Evaluating factors associated with unknown SEER Summary Stage 2000 derived from collaborative stage at central
Journal of Registry Management
|February 28, 2013
Summary
Cancer stage data quality varies across registries. Reporting source significantly impacts unknown cancer stage for most sites, except lung cancer, highlighting data improvement needs.
Area of Science:
- Oncology
- Cancer Epidemiology
- Health Informatics
Background:
- Cancer stage is crucial for prognosis and treatment planning.
- Significant variations exist in unknown stage cancer cases across state registries.
- Factors influencing these variations remain under-researched.
Purpose of the Study:
- To investigate demographic, clinical, and facility-type factors influencing unknown cancer stage percentages.
- To identify key predictors of unknown stage across different cancer types.
Main Methods:
- Analysis of invasive colorectal, lung, female breast, and prostate cancer data (2004-2007) from 47 US registries.
- Utilized Summary Stage 2000 codes and Collaborative Stage Version 1 (CSv1).
- Employed relative importance analysis and multiple linear regression to assess variable associations with unknown stage.
Main Results:
- Lung cancer showed the highest unknown stage percentage (8.3%); prostate cancer had the widest variation (0.6%-18.1%).
- Non-microscopic confirmation, non-hospital reporting, and specific histology (NOS) were associated with higher unknown stage.
- Reporting source was a significant predictor for colorectal, female breast, and prostate cancers, but not lung cancer after adjustment.
Conclusions:
- Factors associated with unknown cancer stage are cancer-site specific.
- Reporting source is a key determinant of unknown stage for most cancers studied.
- Registries with high unknown stage percentages require data quality assessment and targeted training.
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