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Updated: May 13, 2026

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Single-Molecule Fluorescence Visualization of DNA Polymerase Dynamics at G-Quadruplexes
Published on: April 4, 2025
Enzyme-free unlabeled DNA logic circuits based on toehold-mediated strand displacement and split G-quadruplex
Jinbo Zhu1, Libing Zhang, Tao Li
1State Key Laboratory of Electroanalytical Chemistry, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun, Jilin, P R China.
Advanced Materials (Deerfield Beach, Fla.)
|March 1, 2013
Abstract:
Adopting fluorescence of PPIX enhanced by a split G-quadruplex and toehold mediated strand displacement reaction, a series of unlabeled fluorescent logic gates is set up and some of them are cascaded into circuits. Controlled release of PPIX, which is also a photosensitizer in photodynamic diagnosis and therapy, is realized by this circuit, making it a wise choice for DNA computing.

