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Updated: May 13, 2026

Genetically-encoded Molecular Probes to Study G Protein-coupled Receptors

Genetically-encoded Molecular Probes to Study G Protein-coupled Receptors

Published on: September 13, 2013

New mandates? No problem for The Rockefeller University Press.

The Journal of General Physiology

|March 12, 2013

Summary

This summary is machine-generated.

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Epigenetic Regulation

Epigenetic Regulation

Epigenetic mechanisms play an essential role in healthy development. Conversely, precisely regulated epigenetic mechanisms are disrupted in diseases like cancer.

Epigenetic Regulation

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Epigenetic changes alter the physical structure of the DNA without changing the genetic sequence and often regulate whether genes are turned on or off. This regulation ensures that each cell produces only proteins necessary for its function. For example, proteins that promote bone growth are not produced in muscle cells. Epigenetic mechanisms play an essential role in healthy development. Conversely, precisely regulated epigenetic mechanisms are disrupted in diseases like cancer.
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Hardy-Weinberg Principle

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Radiation Pressure: Problem Solving

Radiation Pressure: Problem Solving

The radiation pressure applied by an electromagnetic wave on a perfectly absorbing surface equals the energy density of the wave. The wave's momentum also gets transferred to the surface when an electromagnetic wave is entirely absorbed by it. The rate at which momentum is transmitted to an absorbing surface perpendicular to the propagation direction equals the force on the surface.
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Prokaryotic Transcriptional Activators and Repressors

Prokaryotic Transcriptional Activators and Repressors

The organization of prokaryotic genes in their genome is notably different from that of eukaryotes. Prokaryotic genes are organized, such that the genes for proteins involved in the same biochemical process or function are located together in groups. This group of genes, along with their regulatory elements, are collectively known as an operon. The functional genes in an operon are transcribed together to give a single strand of mRNA known as polycistronic mRNA.
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Prokaryotic Transcriptional Activators and Repressors

Prokaryotic Transcriptional Activators and Repressors

The organization of prokaryotic genes in their genome is notably different from that of eukaryotes. Prokaryotic genes are organized, such that the genes for proteins involved in the same biochemical process or function are located together in groups. This group of genes, along with their regulatory elements, are collectively known as an operon. The functional genes in an operon are transcribed together to give a single strand of mRNA known as polycistronic mRNA.
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Our journals comply with new public access policies. We permit unrestricted text and data mining by all entities, including commercial ones, to ensure broad accessibility.

Area of Science:

Biomedical publishing
Scientific communication
Open access policies

Background:

The Journal of Cell Biology, The Journal of Experimental Medicine, and The Journal of General Physiology journals' existing public access policy aligns with Research Councils UK (RCUK) and Wellcome Trust mandates.
New policies from RCUK and Wellcome Trust include specific licensing terms for third-party content reuse, particularly for text and data mining.

Discussion:

The necessity of these specific licensing terms for reuse is questioned.
Journals have updated their licensing policy to explicitly permit text and data mining of published content by any party.
This includes commercial entities, ensuring maximum data accessibility.

Key Insights:

Full compliance with Research Councils UK (RCUK) and Wellcome Trust public access policies.

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Last Updated: May 13, 2026

Genetically-encoded Molecular Probes to Study G Protein-coupled Receptors

Genetically-encoded Molecular Probes to Study G Protein-coupled Receptors

Published on: September 13, 2013

Cell Culture Techniques and Practices to Avoid Contamination by Fungi and Bacteria in the Research Cell Culture Laboratory

Cell Culture Techniques and Practices to Avoid Contamination by Fungi and Bacteria in the Research Cell Culture Laboratory

Published on: July 7, 2023

Direct Restart of a Replication Fork Stalled by a Head-On RNA Polymerase

Direct Restart of a Replication Fork Stalled by a Head-On RNA Polymerase

Published on: April 29, 2010

Proactive policy update to permit unrestricted text and data mining.

Enhancing accessibility of published research for all users.

Outlook:

Encouraging broader data and text mining for scientific advancement.
Facilitating new research through open access and flexible licensing.
Setting a precedent for open scientific data sharing practices.