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Updated: May 13, 2026

Midface Hypoplasia and Cranial Base Morphology in Syndromic Craniosynostosis: A Comparative Analysis Study Using a Predictive Regression Model
Published on: November 4, 2025
[Cephalometry study of craniofacial growth in mixed dentition with OSAHS children]
Weizhi Wang1, Yan Wang, Xin Wang
1Department of Stomatology, Qilu Hospital, Shandong University, Jinan 250012, China. zww_919@126.com
Objective:
To investigate the craniofacial growth characteristics in mixed dentition of OSAHS and simple snoring (SS) children.
Method:
Craniofacial morphology was studied by computerized cephalometric analysis in 24 children with OSAHS, 12 children with simple snoring and 34 healthy children.
Result:
In OSAHS children, SNB (75.83 +/- 2.92) was significantly smaller than healthy children (P < 0.05), while ANB (5.83 +/- 2.76), Y axis angle (72.05 +/- 2.99), FH-MP (34.68 +/- 5.05), UI-SN (107.49 +/- 5.04) and LI-MP (98.38 +/- 5.28) were larger in comparison with healthy children (with the P values P < 0.01, P < 0.01, P < 0.01, P < 0.05 and P < 0.05, respectively). The GoGn in OSAHS children (57.20 +/- 5.64) was smaller than healthy children (P < 0. 05). In SS children, the indexes ANB (5.34 +/- 1.86), Y axis angle (67.42 +/- 4.53), FH-MP (31.62 +/- 4.60) and LI-MP (98.46 +/- 5.28) were also significantly larger than healthy children (with the P values P < 0.05, P < 0.01, P < 0.05 and P < 0.01, respectively). The GoGn in SS children (58.92 +/- 5.27) was also smaller (P < 0.05) than healthy children. All these indexes showed no significant differences between OSAHS children and SS children.
Conclusion:
The effects of OSAHS and SS on craniofacial growth of children in mixed dentition include posterior displacement and shortening of mandible, heightening of anterior face and the labial inclination of maxillary central incisors and mandible central incisors. The change of breath mode was the main cause of these malformations.
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