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High myopia-partial reduction orthokeratology (HM-PRO): study design.
1School of Optometry, The Hong Kong Polytechnic University, Hong Kong. jessie@eyecare.com.hk
Summary
Partial reduction orthokeratology (PR ortho-k) successfully reduced myopia in high myopic children. This pilot study found PR ortho-k safe and effective for myopia control with no significant impact on ocular health.
Area of Science:
- Ophthalmology
- Optometry
- Corneal Refractive Therapy
Background:
- High myopia in children poses significant risks for ocular health complications.
- Orthokeratology offers a potential method for myopia management.
- Partial reduction orthokeratology (PR ortho-k) is an emerging technique for myopia control.
Purpose of the Study:
- To evaluate the design and preliminary outcomes of a pilot study on high myopia management using partial reduction orthokeratology (PR ortho-k).
- To assess the efficacy and safety of PR ortho-k in children with high myopia.
Main Methods:
- A pilot study randomly assigned 52 children with high myopia (≥6.00D) to either PR ortho-k or a spectacle control group.
- PR ortho-k involved custom 4-zone lenses targeting a 4.00D reduction, with residual refractive errors corrected by single vision spectacles.
- Subjects underwent assessments after overnight wear, one week, and one month post-lens wear.
Main Results:
- Nineteen (79%) PR ortho-k subjects achieved successful lens fit within one month, with a median myopic reduction of 3.75D.
- The incidence of mild corneal staining decreased from 30% after the first wear to 16% at one month.
- Corneal pigmented arc was observed in 32% of PR ortho-k subjects at the one-month follow-up.
Conclusions:
- Partial reduction orthokeratology (PR ortho-k) is a viable treatment for high myopia in children.
- PR ortho-k demonstrated successful application with no significant adverse effects on ocular health or best-corrected visual acuity after one month.
