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Updated: May 13, 2026

Intravitreal Injection and Quantitation of Infection Parameters in a Mouse Model of Bacterial Endophthalmitis
Published on: February 6, 2021
Bilateral Candida endophthalmitis in a premature infant
Rebecca A Manning1, Joshua N Carlson, Eric W Hein
1Department of Ophthalmology, Wake Forest Baptist Medical Center, Winston-Salem, North Carolina 27157, USA.
Abstract:
Endogenous infantile Candida endophthalmitis is a rare but potentially devastating condition resulting from sequestration of the fungus within the lens after systemic infection. We report the case of a 20-week-old girl with a history of Candida sepsis who presented with bilateral Candida albicans endophthalmitis 15 weeks after completing a 6-week course of intravenous antifungal therapy. Prompt vitrectomy resulted in salvage of the right eye, although a total retinal detachment occurred. Cataract extraction and administration of intravenous and intravitreal amphotericin B preserved vision in the left eye.
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