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Using surface-assisted laser desorption/ionization mass spectrometry to detect ss- and ds-oligodeoxynucleotides

Wen-Tsen Chen1, Ming-Feng Huang, Huan-Tsung Chang

  • 1Department of Chemistry, National Taiwan University, Taipei, Taiwan.

Journal of the American Society for Mass Spectrometry
|March 30, 2013
PubMed
Summary

This study introduces a novel method using HgTe nanostructures with SALDI-MS for detecting DNA strands. The technique achieves sensitive, reliable detection of both single- and double-stranded oligodeoxynucleotides.

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