Kisspeptin and puberty in mammals

Ei Terasawa1, Kathryn A Guerriero, Tony M Plant

  • 1Wisconsin National Primate Research Center, University of Wisconsin, Madison, WI 53715-1299, USA. terasawa@primate.wisc.edu

Summary

Kisspeptin signaling is crucial for puberty onset by acting as a component of the GnRH pulse generator. Arcuate nucleus kisspeptin neurons are integral to this mechanism, not regulatory controllers of pubertal timing.

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