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Updated: May 12, 2026

A Stably Established Two-Point Injection of Lysophosphatidylcholine-Induced Focal Demyelination Model in Mice
Published on: May 11, 2022
Mimics and rare presentations of pediatric demyelination
Julia O'Mahony1, Manohar Shroff, Brenda Banwell
1Divison of Neurology, Department of Pediatrics, Research Institute, The Hospital for Sick Children, Toronto, Ontario, Canada.
Abstract:
This article reviews the features that should prompt consideration of diseases that mimic acquired demyelinating syndromes and multiple sclerosis using vignettes to highlight unusual clinical and radiologic features. Cases of transverse myelitis, spinal infarction, acute disseminated encephalomyelitis, fever-induced refractory epileptic encephalopathy in school-aged children, small-vessel vasculitis, Griscelli syndrome type 2, cysticercosis, vitamin B12 deficiency, and chronic relapsing inflammatory optic neuropathy are presented.
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